USCO, also known as the Company of US or US Company, was a group of artists, poets, filmmakers, engineers, and composers who formed a multimedia collective in 1963. Two of its cofounders—Michael Callahan (b. 1944), an electronics innovator and president of Museum Technology Source, and Gerd Stern (b. 1928), a poet, media artist, and president of Intermedia Foundation—reflect on their lives and the creation of USCO. Callahan and Stern discuss their artistic journeys and initial collaborations, which led to the formation of this innovative and technologically prescient multimedia collective. They provide insight into USCO’s influences and activities during the 1960s. Archival footage and behind-the-scenes access to their visit to the National Gallery of Art in preparation for their performance on March 3, 2019, provide a greater context for understanding USCO’s collaborative spirit, rich history, and art practice.